Azithromycin combination therapy for community-acquired pneumonia: propensity score analysis
نویسندگان
چکیده
منابع مشابه
Combination antibiotic therapy for community-acquired pneumonia
Community-acquired pneumonia (CAP) is a common and potentially serious illness that is associated with morbidity and mortality. Although medical care has improved during the past decades, it is still potentially lethal. Streptococcus pneumoniae is the most frequent microorganism isolated. Treatment includes mandatory antibiotic therapy and organ support as needed. There are several antibiotic t...
متن کاملEvaluating combination therapy in community-acquired pneumonia.
It is unclear whether the study by Brown et al (May 2003)1 either “confirms the value of dual therapy,” or that previous investigations have “verified” the benefits of combination therapy in community-acquired pneumonia (CAP). While the accompanying editorial2 points out that many of the studies of combination therapy in CAP are retrospective, another issue complicating interpretation of these ...
متن کاملChoosing the right combination therapy in severe community-acquired pneumonia
Recent studies have suggested that combination antibiotic therapy is preferable to monotherapy for severe community-acquired pneumonia (CAP). In this issue Mortensen and colleagues present retrospective data suggesting that combination therapy with a cephalosporin and a fluoroquinolone is inferior to combination therapy with a cephalosporin and a macrolide. Several mechanisms exist by which qui...
متن کاملCorticosteroid therapy for severe community-acquired pneumonia: a meta-analysis.
BACKGROUND The debate about the efficacy of corticosteroids in the treatment of severe community-acquired pneumonia (CAP) is still a longstanding dilemma. We performed a meta-analysis including 4 randomized controlled trials (RCTs) to evaluate the effect of corticosteroids on the treatment of severe CAP in adults. METHODS We performed a systematic review of published and unpublished clinical ...
متن کاملThe need for macrolides in hospitalised community-acquired pneumonia: propensity analysis.
The present study compared beta-lactam macrolide ("combination") therapy versus beta-lactam alone ("monotherapy") for hospitalised community-acquired pneumonia, using propensity scores to adjust for the differences between patients. A prospective multinational observational study was carried out. Baseline patient and infection characteristics were used to develop a propensity score for combinat...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2019
ISSN: 2045-2322
DOI: 10.1038/s41598-019-54922-4